The Osmolyte Taurine Protects against Ultraviolet B Radiation-Induced Immunosuppression

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The osmolyte taurine protects against ultraviolet B radiation-induced immunosuppression.

Organic osmolytes, such as taurine, are involved in cell volume homeostasis and cell protection. Epidermal keratinocytes possess an osmolyte strategy, i.e., they take up taurine upon hyperosmotic stress and express the corresponding transporter TAUT. UVB irradiation also triggers taurine uptake and TAUT expression in this cell type. We therefore asked whether taurine plays a role in photoprotec...

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ژورنال

عنوان ژورنال: The Journal of Immunology

سال: 2007

ISSN: 0022-1767,1550-6606

DOI: 10.4049/jimmunol.179.6.3604